Contraindications and side effects
Regardless of the form of release of the described drug, there are a number of cases when it is better not to use it for the treatment or prevention of parasitic diseases of a particular animal.
In particular, this applies to the following cases:
- in weakened and exhausted state of animals;
- during pregnancy and lactation of cats;
- up to two months of age for kittens (except for extreme cases of using the Dironet Junior suspension);
- for infectious diseases in animals;
- in case of individual intolerance to individual components of the drug;
- in case of exacerbation of kidney and liver diseases (but in this case it is worth additionally consulting with a specialist).
Side effects from using the Dironet composition are extremely rare, but violating the dosage or using an expired drug threatens poisoning, with the following main symptoms:
- nausea;
- vomiting;
- muscle tremors;
- impaired coordination of movements;
- excessive salivation;
- general weakness.
If several signs from this list appear at once, if possible, it is worth removing the remaining drug from the cat’s body, and if necessary, then use other drugs for symptomatic treatment of the pet.
Important! Before using the drug, it is important to make sure that the cat is in good health and normal well-being, and also to exclude the possibility of using other medications.
Indications for use
According to the instructions, Dironet in tablets and suspensions is used for dogs to combat tapeworms and worms, as well as other types of parasites that affect the gastrointestinal tract.
It is prescribed in the following cases:
- For preventive deworming, which is carried out every few months.
- For the treatment of nematodes and cestoses at any stage of development.
- For the prevention of dirofilariasis (active substances negatively affect microfilariae).
The drug in drops has more indications:
- Prevention and treatment of worms (worms and tapeworms).
- Prevention of dirofilariasis.
- Prevention of infestation and destruction of fleas, lice and lice.
- Prevention and destruction of demodectic and sarcoptoid mites.
After penetration into the gastrointestinal tract or application to the skin (depending on the form), the active substances of the drug are absorbed into the bloodstream and distributed to all organs and systems. Due to the fact that the maximum concentration is reached after 4-9 hours, the drug is effective.
How to use
Features of using Dironet for cats depend on the form of release and the concentration of active components, so before starting treatment, carefully read the instructions for use.
Suspension
When treating helminthic infestations, the medicine is given once. It is advisable to do this before morning feeding. The dosage is calculated simply - 1 ml of suspension per 1 kg of animal. When using the drug for kittens whose weight has not exceeded 0.5 kg, the medicine must be mixed with 0.3 ml of boiled cold water.
Since the product has the aroma and taste of salmon, most cats will eat it without problems. You can force the suspension out of the syringe onto the root of the tongue. If this is too stressful for your pet, then it is better to mix the medicine with the food (in a small amount). Before use, the antiparasitic agent must be shaken well, as it tends to separate.
If the medicine is used for prevention, it is given once every three months, as well as before vaccinations and mating. It is not necessary to limit the animal’s food the day before or give it a laxative before using Dironet.
Note! The dosage of Dironet Junior is calculated in the same way, but the suspension can be used for kittens from 3 weeks of age
Pills
The dosage of anthelmintic tablets is calculated as follows - 1 piece per 10 kg of weight. It is not recommended to give the medicine to small kittens, since measuring out the right amount is quite difficult.
The tablets are given forcibly or fed mixed with food. When treating nematodes and cestodes, it is given once; for prevention, the procedure is repeated quarterly.
Drops spot-on
The drops are packaged in polymer pipette tubes, so they are convenient to use. You just need to break off the tip and apply the contents to the withers, dripping in 3-4 places that are inaccessible for licking. For kittens, the dose is 0.1 ml per 1 kg of body weight. When applying, adhere to the following doses:
- for animals less than 1 kg – 3 drops;
- for pets over 1 kg – 5 drops.
For adult cats, the dose is 0.2 ml per 1 kg of weight. When purchasing medicine, consider the weight of the animal to select pipettes of the appropriate size.
Depending on the pathology, the following application regimens are used:
- To get rid of fleas or lice, the drug is applied to the skin once, to prevent infection - once a month.
- When treating ear mites, the medicine is dripped onto the skin once. If necessary, repeat the procedure after a month. If complications occur, antibiotics and other medications may additionally be used.
- For notoedrosis and sarcoptic mange, drops are applied 2-4 times with an interval of 12-14 days. To prevent relapse, repeat the procedure after a month.
- If the main purpose of use is the prevention of worms, the drug is used once a month.
Note! After applying the drops, the animal should not be bathed for 4 days.
Dosage and method of application:
The drug is used by animals by drip (“spot-on”) application to dry, intact skin. Before use, break off the tip of the pipette tube and, parting the fur, apply the drug to the animal’s skin along the spine, in places inaccessible for licking, in the neck area at the base of the skull or between the shoulder blades. When treating large animals, the contents of the pipettes are applied to the skin in 3-4 places. Depending on the weight of the animal, the drug “Dironet spot-on” is used in various packaging in the doses indicated in the table. The minimum therapeutic dose of the drug for adult animals is 0.2 ml/kg of animal weight, which corresponds to 17 mg/kg of praziquantel and 4 mg/kg of ivermectin for dogs; for cats – 17 mg/kg praziquantel and 1 mg/kg ivermectin. The minimum therapeutic dose of the drug for puppies and kittens is 0.1 ml/kg body weight, which corresponds to 8.5 mg/kg praziquantel and 2 mg/kg ivermectin for puppies, 8.5 mg/kg praziquantel and 0.5 mg/kg ivermectin for kittens. mg/kg ivermectin. Taking into account the type, age and weight of the animal being treated, a pipette tube of the required volume or a combination thereof is selected.
Animal weight | Drug dose, number of pipettes | ||||||||||
Adult dogs: | |||||||||||
from 2 kg to 5 kg | 1 | ||||||||||
from 5 kg to 10 kg | 2 | ||||||||||
from 10 kg to 20 kg | 3 | ||||||||||
from 20 kg to 30 kg | 4 | ||||||||||
more than 30 kg | 5 |
Dironet for dogs
"Dironet" is a broad-spectrum anthelmintic. It is distinguished by its versatility, since it not only destroys worms and tapeworms, but is also suitable for pets of large and small breeds. The medicine is produced domestically, which determines its affordable price. And although the product is considered low-hazard, before using Dironet for dogs, read the instructions.
Intended to combat helminths and other parasites, the drug is available in several forms:
- in tablets;
- in suspension;
- in drops.
Tablets and suspension are intended for internal use, and drops are used for external treatment. They differ in composition and are used not only for deworming, but also for the destruction and prevention of ectoparasites. They have a wider spectrum of action. Oral preparations have a meaty aroma, so animals consume them with pleasure.
The tablets are packaged in blisters of 6 pieces. The suspension is sold in polymer bottles with a volume of 10 ml. The drug comes with not only instructions, but also a syringe, which makes it easy to measure the required amount of product. The drops are packaged in polymer pipettes of various sizes. They have a simple and convenient form for use.
Dironet, intended for internal use, contains the following active substances:
- Pyrantel pamoate – blocks the transmission of nerve impulses, leading to disruption of the nervous system of parasites. In addition, it contributes to the destruction of the cell membrane, which causes the death of adult individuals.
- Ivermectin - affects the nervous system and muscle membrane of parasites. When maximum concentration in the body is reached, it causes paralysis and death.
- Praziquantel - affects cestodes, disrupting metabolic processes in their body. Due to increased permeability of the cell membrane, as well as disruption of muscle function, the death of parasites occurs.
The drops for external use do not contain pyrantel pamoate, otherwise the active substances are identical.
According to the instructions, Dironet in tablets and suspensions is used for dogs to combat tapeworms and worms, as well as other types of parasites that affect the gastrointestinal tract.
It is prescribed in the following cases:
- For preventive deworming, which is carried out every few months.
- For the treatment of nematodes and cestoses at any stage of development.
- For the prevention of dirofilariasis (active substances negatively affect microfilariae).
The drug in drops has more indications:
- Prevention and treatment of worms (worms and tapeworms).
- Prevention of dirofilariasis.
- Prevention of infestation and destruction of fleas, lice and lice.
- Prevention and destruction of demodectic and sarcoptoid mites.
After penetration into the gastrointestinal tract or application to the skin (depending on the form), the active substances of the drug are absorbed into the bloodstream and distributed to all organs and systems. Due to the fact that the maximum concentration is reached after 4-9 hours, the drug is effective.
Release form of the drug Dironet spot they composition
Dironet Spot-on is available in the form of transparent drops that have a sharp and specific odor and a yellowish tint. It is packaged in plastic pipettes, each with a capacity of 1 ml. It goes on sale in cardboard boxes. Each of them contains instructions and 3 pipettes with the drug.
The drops contain the following substances:
- Ivermectin (5 mg) – has a detrimental effect on external parasites (ticks, fleas, lice).
- Praziquantel (85 mg) – destroys tapeworms and roundworms.
The drug is available in suspension and tablets for cats and dogs.
The cost of the drug is low: from 240 to 320 rubles per package with three pipettes (the price depends on the region). You can purchase Dironet Spot-on at a veterinary pharmacy or pet store.
There are several analogues of the drug with a similar mechanism of action and method of application (drops on the withers):
- Prazicide complex (ivermectin, levamisole, praziquantel, thiamethoxam) – from 150 to 180 rubles. per pipette.
- Stronghold (selamectin) – from 700 to 800 rubles. for 3 pipettes.
- Lawyer (moxidectin, imidacloprid) – from 800 to 1300 rubles. for 3 pipettes.
- In-Up (fipronil, praziquantel, aversectin) – 170-200 rubles. per bottle 1 ml.
The drug for cats in the form of drops Dironet Spot-on is an effective and at the same time inexpensive remedy that destroys both internal and external parasites.
The advantages include ease of application, the disadvantages are the prohibition on treating pregnant and lactating animals. The drug is distributed everywhere, which means there will be no difficulties in purchasing it.
The package contains 3 pipettes. Its price is about 300 rubles. You can buy the medicine at a veterinary pharmacy or pet store. It does not require a veterinarian's prescription. The drug for kittens and adult animals costs the same.
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There are analogues of drops, the most common of them are:
- Prazicide Complex - the drug is more expensive and costs 180-200 rubles per pipette.
- Lawyer - a pack of 3 pipettes will cost 1000 rubles.
- Stronghold - 3 pipettes cost about 800 rubles.
- In-Up Complex - a 1 ml package costs about 200 rubles.
Comparing prices, we can say that Dironet Spot-on is the cheapest anti-parasite remedy for cats and at the same time highly effective.
The drug destroys adults, larvae and eggs of helminths, roundworms and nematodes; subcutaneous, nasopharyngeal and cutaneous parasites, lice and fleas, ticks.
The active substance affects the nervous system of the parasite and causes its death.
After administration, the medicine is quickly absorbed and distributed in the tissues and organs of the animal. The drug continues for 10-14 days. Residues of the drug are excreted in the urine and partially in bile. During lactation, Dironet penetrates into milk.
After using the drug, the active substances spread in the upper layers of the skin and accumulate in the hair follicles and sebaceous glands. Part of the medicine enters the bloodstream and internal organs of the animal.
Dironet spot, in a short time, rids the cat of helminths and external parasites. The use of the product is suitable if it is not possible to give the animal a tablet or suspension.
DIRONET 200 anthelmintic for kittens and adult cats, pack of 10 tablets AVZ
A complex anthelmintic drug for kittens and adult cats for the prevention of dirofilariasis, as well as for the treatment and prevention of nematodes and cestodiases.
Dironet 200 is prescribed to adult cats and kittens starting from 3 weeks of age and weighing from 0.5 kg for cestodiases and nematodes of the gastrointestinal tract for therapeutic and prophylactic purposes.
Indications:
- Helminthiasis.
- Prevention of dirofilariasis.
Key Features:
- The widest spectrum of anthelmintic action.
- High efficiency.
- Convenient dosage for animals of different body weights.
- Allowed for kittens over 3 weeks of age and weighing more than 0.5 kg.
Compound:
Pyrantel pamoate – 60 mg/tablet, praziquantel – 20 mg/tablet, ivermectin – 0.024 mg/tablet.
DIRONET is a Russian trademark, which since 1993 has been developing and producing medicines for animals.
General information:
Trade name of the drug: Dironet 200 (Dironet 200).
International nonproprietary names of active ingredients: pyrantel pamoate, praziquantel, ivermectin.
Dosage form: tablets for oral use
Pharmacological properties:
Dironet 200 contains in one biconvex tablet pyrantel pamoate 60 mg, praziquantel 20 mg and ivermectin 0.024 mg. Dose - 1 tablet per 4 kg of animal body weight.
Dironet 200 has a wide spectrum of nematocidal and cestodocidal action, is active against round and tape helminths parasitizing dogs and cats, including Toxocara canis, T. cati, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus , E. multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp., as well as larval developmental phases (microfilaria) of Dirofilaria immitis and Dirofilaria repens.
The mechanism of action of ivermectin is by binding to glutamate-dependent chloride channels located primarily in the swallowing and somatic muscles. As a result, the permeability of the membrane for chlorine ions increases, the transmission of neuromuscular impulses is blocked, paralysis and death of the parasite occurs.
The mechanism of action of pyrantel pamoate is to block neuromuscular transmission, disrupt the permeability of cell membranes and inhibit cholinesterase, which also leads to paralysis and death of the parasite.
The mechanism of action of praziquantel is based on disruption of glucose transport and microtubular function in cestodes, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes and disruption of muscle innervation.
Doses and order of application:
For cestodiases and nematodes of the gastrointestinal tract, Dironet 200 is used individually orally once in the morning feeding for therapeutic and prophylactic purposes in the following doses: pyrantel pamoate - 15 mg/kg, praziquantel - 5 mg/kg, ivermectin - 0.006 mg/kg, based on 1 tablet Dironet 200 per 4 kg of body weight of cats and kittens.
For preventive purposes, deworming is carried out quarterly, as well as before each vaccination.
To reduce the number of microfilariae circulating in the blood of animals infected with D. immitis or D. repens, the drug is prescribed in a therapeutic dose once, once a month.
In order to prevent dirofilariasis in a region unfavorable for the disease, Dironet 200 is used in the spring-summer-autumn period: once before the start of mosquito summer (March-April), then monthly from April to October, and the last time in the season 1 month after the end of summer mosquitoes (October-November).
Contraindications:
The use of the drug is prohibited for females during pregnancy and lactation, as well as for kittens under 3 weeks of age. The drug should not be used in animals weighing less than 0.5 kg.
Side effects:
When using the drug according to the instructions, no side effects or complications are observed.
Release form:
Dironet 200 tablets - blisters of 10 tablets.
Outer packaging: cardboard box.
Storage:
Dironet 200 tablets are stored in the manufacturer's sealed packaging, protected from light and moisture, separate from food and feed, at a temperature of 0°C to 25°C, inaccessible to children and animals.
Quantity per package: 10 tablets.
Country of origin: Russia. Information about the composition and ingredients, color scheme, technical and other characteristics, country of origin, appearance and delivery package of the product is for reference only and is based on the latest information available at the time of publication. Delivery of this product is carried out to all regions of the Russian Federation.
Composition and pharmacological properties.
The drug as active ingredients in 1 ml, depending on the modification, respectively contains: “Dironet spot-on” for dogs – 85 mg of praziquantel and 20 mg of ivermectin, “Dironet spot-on” for cats – 85 mg of praziquantel and 5 mg of ivermectin, and also excipients.
"Dironet Spot-on" has a wide spectrum of antiparasitic action, is active against larval and mature stages of development of intestinal nematodes, including Toxocara canis, Toxocara cati, Toxascaris leonina, Ancylostoma spp., Uncinaria stenocephala, Trichuris vulpis, cestodes, including Echinococcus granulosus, Echinococcus multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp., Mesocestoides lineatus, fleas (Ctenocephalides spp.), lice (Linognatus setotus), lice (Trichodectes canis), sarcoptoids (Sarcoptes canis, Otodectes cynotis, Notoedres cati) and demodectic mites (Demodex canis) parasitize dogs and cats.
After cutaneous application, the drug, absorbed from the site of application, enters the systemic bloodstream, organs and tissues of the animal, providing an effective antiparasitic effect.
It has an insectoacaricidal effect on fleas, lice, lice, sarcoptic and demodectic mites present on animals at the time of treatment.
The mechanism of action of ivermectin, which is part of the drug, is its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chloride channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of impulses, which leads to paralysis and death of ectoparasites and nematodes.
The mechanism of action of praziquantel is based on the depolarization of neuromuscular ganglion blockers, disruption of glucose transport and microtubular function of all phases of cestode development, which causes disruption of muscle innervation, paralysis and death of parasites.
Analogues of the drug according to release form, indications for use
The manufacturer of the solution claims that Stronghold has no analogues. However, in veterinary pharmacies you can find IN-AP (a special treatment complex), which is as similar as possible to Stronghold. There are several indications for the use of such drugs:
- Bars spot-on;
- Inspector (Inspector Total K);
- Adventage;
- Dironet spot-on.
If you want to independently choose an analogue of the prescribed drug, it is better to first consult with a veterinarian. When I have to select medications for my cats, but there is no opportunity to visit a veterinary clinic, I call our regular veterinarian (this is very convenient - if you are always observed and treated by the same specialist, he will remember the characteristics of your pet). In addition, I believe that sellers in veterinary pharmacies try to retain every customer, so they often offer drugs with a higher price instead of a good analogue.
Comparison table: Stronghold and other parasite control drugs
Name | Active substance | Indications for use | Safety | Release form | Price |
Stronghold | selamectin | toxocariasis, the presence of fleas, lice, lice, hookworm, otodectosis, dirofilariasis, flea dermatitis, sarcoptic mange | You can wash your cat after 2 hours, pipettes with a lid | solution (drops) in pipettes of 0.25, 0.5, 0.75 ml and 1.2 ml | from 450 rubles for 1 pipette |
Bars spot-on | praziquantel, ivermectin | toxocariasis, hookworm disease, echinococcosis, diphyllobothriasis and other helminthiases, fleas, lice, lice and ticks (demodectic, sarcoptic) | You can wash your cat only after 4 days, pipettes without a lid | solution (drops) in disposable pipettes of 0.2, 0.3, 04 and 0.5 ml, 1 and 2 ml | from 150 rubles for 2 pipettes |
Inspector Total K | fipronil, moxidectin | fleas, lice eaters, ixodid ticks, notoedrosis, dirofilariasis, toxocariasis, toxascariasis, uncinariasis, hookworm | the cat should not be touched for 2–3 days after treatment | oily solution in pipettes of 0.4 and 0.8 ml | from 290 rubles for 1 pipette 0.4 ml |
Adventage | imidacloprid | presence of fleas, lice, lice | the cat should not be touched for 24 hours after application | solution in pipettes with caps of 0.4 and 0.8 ml | from 205 rubles for 1 pipette 0.4 ml |
IN-AP complex (IN-AP complex) | praziquantel, fipronil, aversectin C1 | entomosis caused by fleas, lice, lice, damage by ixodid ticks, cestodosis and nematodosis, dirofilariasis (prevention) | Direct contact with the medicine should be avoided (may be an allergy) | solution in bottles with a dispenser cap or pipettes of 1 ml | from 220 rubles for 1 bottle/pipette |
Contraindications and precautions
As a precaution, it is necessary to apply the preparation for external use only to dry and intact skin. After the manipulations, the animal should not be washed for at least 4 days.
It is not recommended to give your cat other medicinal formulations against helminths and external parasites during treatment with Dironet. Contraindications include: early age (less than 60 days after birth) - unless the instructions provide otherwise; pregnancy and lactation period; infection of the body; rehabilitation period after a long illness; strong sensitivity of the body to some components of the drug.
Contraindications and side effects
Contraindications to the use of Dironet of any modification are:
- puppies are less than 3 weeks old for tablets and suspensions, less than 2 months for drops;
- sheltie, bobtail, collie and boxer dog breeds, due to hypersensitivity to macrocyclic lactones of ivermectin;
- pregnancy and lactation period;
- exhaustion;
- presence of serious chronic diseases;
- fragile condition after illness or its presence;
- individual intolerance to the drug.
Consultation with a veterinarian is recommended before use.
Side effects and symptoms of overdose:
- vomit;
- diarrhea;
- lethargy;
- lack of coordination;
- refusal of food;
- profuse salivation.
If a negative reaction occurs, it is necessary to show the animal to a doctor and take enterosorbents.
Instructions for use and dosage
The dosage calculation depends on the age and weight of the animal, as well as on the form of release of the purchased drug.
Drops
Spot on drops for cats are presented in the form of a yellowish liquid contained in a plastic tube. The product helps fight worms, lice, and scabies mites. After treatment, it begins to actively penetrate the epidermis, and then into the blood, thereby contributing to the death of pathogenic microorganisms.
Dironet spot drops for treating cats
According to the instructions for use, Dironet is prescribed for pets with the following problems:
- intestinal nematode;
- cestodiasis;
- otodectosis;
- demodex.
Dironet drops on the withers for cats are applied to dry and pre-prepared skin of the animal.
Particular attention is paid to hard-to-reach places: neck, shoulder blades. For every kilogram of a cat take up to 1.2 ml of the drug
When killing fleas, drops are used once. For more serious diseases, treatment is carried out 2-4 times. In some cases, the dosage may vary.
Features of application
Dironet Spot-on for cats, instructions:
- If fleas or ticks do not disappear after applying drops to the skin once, it is recommended to re-treat after 1 week. In this case, it is necessary to observe the specified proportions.
- Ear mites are removed once using a special stick dipped in Dironet drops. If complications arise during treatment, it is recommended to take auxiliary medications.
- If mites have affected the entire body, treat with drops 2 times a day (morning and evening), repeat the procedure after 10-15 days.
- For preventive purposes, the product is applied to the skin once every 4 months.
Important! The drops can cause excessive tearing in the animal due to the aggressive chemical composition. Therefore, it is important that they do not get into the cat's eyes.
Suspension
Suspension for kittens is intended to eliminate helminthic diseases. The product is presented in the form of a yellowish liquid substance. Dironet Junior is intended for small animals, so its active ingredients include pamoate, sodium ribonucleate and nipazole. These substances have a gentle effect on the kittens’ body, remove parasites from them and restore the functioning of the gastrointestinal tract.
Important! The suspension strengthens the immune system and prevents the development of seasonal diseases. The drug is prescribed for the following pathologies:
The drug is prescribed for the following pathologies:
- uncinariasis;
- toxocariasis;
- trichocephalosis.
Suspension
Dironet for kittens: the instructions suggest using the product at the rate of 1 suspension per 10 kg of cat weight. If the pet's weight is less, then the tablet is divided in half. The duration of treatment depends on the pathology.
Tablets: selection of doses, dosage regimen
Dironet tablets for cats are presented in the form of a round product with a grayish tint. They contain pamoate, ivermactin, and potato starch. The combination of these substances has a deadly effect on parasites, preventing them from spreading throughout the pet’s body. Pamoate causes paralysis in roundworms, toxocariasis leads to the death of tapeworms. Ivermectin removes fleas and ticks by blocking their motor function. The drug is used for cestodosis and dirofilariasis.
For 10 kg of pet's weight, take 1 tablet of Dironet. The exact timing is determined by the doctor after consultation.
Instructions for use
To apply the medicine, take the tube and cut off the top of its tip with scissors. Use your fingers to spread the fur on the withers and apply drops to the skin between the shoulder blades, where the cat cannot lick them off.
The medicine is applied to the withers so that the pet cannot lick the medicine from another accessible place
When using the drug, the most important thing is to follow the calculated dosage.
Table: dosage of Dironet Spot-on for cats depending on weight and age
Cat weight | Drug dosage, ml |
Kittens older than two months | |
Up to 1 kg | 0.1 ml (3 drops) |
More than 1 kg | 0.2 ml (5 drops) |
Adult cats | |
Up to 5 kg | 1.0 ml |
More than 5 kg | 0.2 ml/kg body weight |
Depending on the disease, Dironet Spot-on is used in different ways:
- To combat lice-eaters, fleas and lice, the drug is applied once. Later, during the warm period of the year with increased insect activity, the procedure is repeated once a month for prevention;
- To kill ear mites (otodectosis), the medicine is used once. During treatment, it is necessary to clean your pet's ears from dirt, crusts and scabs. In case of complications due to the disease, it is necessary to start taking medications aimed against the development of inflammation. The course is repeated every other month if necessary;
- If the pet is infected with ticks, the pet is treated with the medicine 2–4 times with a break between procedures of 10–14 days. To prevent recurrence of the disease, the medicine is used once a month;
- for the treatment of cestodiases and nematodes in the gastrointestinal tract, Dironet Spot-on is used once, and for prevention purposes - once every three months;
- For general skin prevention, the procedure is carried out once every 3–5 months.
Video: how to treat a cat with flea medicine
Doses and order of application
The drug Dironet "Spot-On" is used by drip application to dry, intact skin.
Before use, break off the tip of the pipette tube and, spreading the fur, apply the drug to the skin along the spine, in places inaccessible for licking (in the neck area at the base of the skull or between the shoulder blades).
When processing large individuals, the contents of the pipettes are applied to the skin in 3–4 places.
Depending on the weight of the animal, the drug Dironet “Spot-On” is used in various packaging in the doses indicated in the table.
The minimum therapeutic dose of the drug for adult cats is 0.2 ml/kg of animal weight, which corresponds to 17 mg/kg praziquantel and 1 mg/kg ivermectin.
The minimum therapeutic dose of the drug for puppies and kittens is 0.1 ml/kg body weight, which corresponds to 8.5 mg/kg praziquantel and 2 mg/kg ivermectin for puppies, 8.5 mg/kg praziquantel and 0.5 mg/kg ivermectin for kittens. mg/kg ivermectin.
Taking into account the type, age and weight of the animal being treated, a pipette tube of the required volume or a combination thereof is selected.
Animal weight | Dose of Dironet, number of pipettes |
Puppies from 2 months of age | |
up to 1 kg | 1 |
from 1 kg to 2 kg | 2 |
Adult dogs | |
from 2 kg to 5 kg | 1 |
from 5 kg to 10 kg | 2 |
from 10 kg to 20 kg | 4 |
from 20 kg to 30 kg | 6 |
Kittens from 2 months of age | |
up to 1 kg | 1 |
Adult cats | |
from 2 kg to 5 kg | 1 |
More than 5 kg* | 2 |
Drops on the withers for dogs and puppies over 2 months of age Dironet “Spot-On” Agrovetzaschita are a medicinal product for external use for helminthiasis and arachno-entomosis. Through the application sites, the drug is absorbed and enters the bloodstream, organs and tissues of the animal, effectively affecting parasites.
Drops on the withers for dogs Dironet "Spot-On" are intended for the treatment and prevention of intestinal nematodes, cestodiases, entomoses, otodectosis, sarcoptic mange, notoedrosis and demodicosis. They contain active ingredients (praziquantel and ivermectin), as well as auxiliary components.
Ivermectin affects the current of chlorine ions through the membranes of nerve and muscle cells of the parasite. Its main targets are glutamate-sensitive chloride channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of impulses, which leads to paralysis and death of ectoparasites and nematodes.
Praziquantel depolarizes neuromuscular ganglion blockers, disrupting glucose transport and microtubular function of all phases of cestode development, causing disruption of muscle innervation, paralysis and death of parasites.
Auxiliary components accelerate the process of entry of active substances into the animal’s body.
As an antiparasitic agent, Dironet "Spot-On" for dogs has pronounced activity against larval and mature phases of development of intestinal nematodes, including Toxocara canis, Toxocara cati, Toxascaris leonina, Ancylostoma spp., Uncinaria stenocephala, Trichuris vulpis and cestodes, including Echinococcus granulosus, Echinococcus multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp., Mesocestoides lineatus, as well as fleas (Сtenocephalides spp.), lice (Linognatus setotus), lice (Trichodectes canis), sarcoptoids (Sarcoptes canis, Otodectes cynot is , Notoedrescati) and demodectic mites (Demodex canis) present on the animal at the time of treatment.
The drug is well tolerated by dogs of all breeds and ages.
Indications
"Dironet spot-on" is prescribed to adult dogs and cats, puppies and kittens over 2 months of age for the treatment and prevention of intestinal nematodes, cestodiases, entomoses, otodectosis, sarcoptic mange, notoedrosis and demodicosis.
Dosage and method of administration
The drug is used by animals by drip (“spot-on”) application to dry, intact skin. Before use, break off the tip of the pipette tube and, parting the fur, apply the drug to the animal’s skin along the spine, in places inaccessible for licking, in the neck area at the base of the skull or between the shoulder blades. When treating large animals, the contents of the pipettes are applied to the skin in 3-4 places. Depending on the weight of the animal, the drug “Dironet spot-on” is used in various packaging in the doses indicated in the table. The minimum therapeutic dose of the drug for adult animals is 0.2 ml/kg of animal weight, which corresponds to 17 mg/kg of praziquantel and 4 mg/kg of ivermectin for dogs; for cats – 17 mg/kg praziquantel and 1 mg/kg ivermectin. The minimum therapeutic dose of the drug for puppies and kittens is 0.1 ml/kg body weight, which corresponds to 8.5 mg/kg praziquantel and 2 mg/kg ivermectin for puppies, 8.5 mg/kg praziquantel and 0.5 mg/kg ivermectin for kittens. mg/kg ivermectin. Taking into account the type, age and weight of the animal being treated, a pipette tube of the required volume or a combination thereof is selected
Animal weight | Drug dose, number of pipettes | ||||||||||
Puppies from 2 months of age: | |||||||||||
up to 1 kg | 1 | ||||||||||
from 1 kg to 2 kg | 2 | ||||||||||
Adult dogs: | |||||||||||
from 2 kg to 5 kg | 1 | ||||||||||
from 5 kg to 10 kg | 2 | ||||||||||
from 10 kg to 20 kg | 3 | ||||||||||
from 20 kg to 30 kg | 4 | ||||||||||
more than 30 kg | 5 | ||||||||||
Kittens from 2 months of age: | |||||||||||
up to 1 kg | 1 | ||||||||||
Adult cats: | |||||||||||
from 2 kg to 5 kg | 1 | ||||||||||
more than 5 kg | 2 |
To destroy fleas, lice and lice, the animal is treated once, to prevent re-infestation - once a month throughout the entire season of insect activity. In order to prevent re-infestation by fleas, the animals’ bedding is replaced or treated with the “Bars”, “Bars Forte” insecticidal spray. For long-term protection of the animal from fleas and other ectoparasites, insectoacaricidal drops “Bars”, “Bars Forte” or the insectoacaricidal collar “Bars” are used. To treat otodectosis (ear scabies), the drug is applied to the skin once. If necessary, the course of treatment is repeated after 1 month. During the treatment process, it is recommended to clean the ear canal of exudate and scabs, and in case of complications with otitis media, prescribe antimicrobial and anti-inflammatory drugs. For therapeutic purposes in cases of sarcoptic mange and demodicosis in dogs and notoedrosis in cats, the drug is used 2–4 times with an interval of 10–14 days until double negative results of acarological examination are obtained; in order to prevent possible invasion - 1 time per month. Treatment is recommended to be carried out comprehensively using etiotropic, pathogenetic and symptomatic drugs in accordance with the instructions for their use. For deworming of animals with nematodes and cestodes of the gastrointestinal tract, the drug is used for therapeutic purposes once, for prophylactic purposes - once a quarter.
Description of the drug "Dironet" for cats
“Dironet” is a remedy against worms of various shapes parasitizing inside the body of an animal, called helminths (simply worms). With its help, you can fight endoparasite invasion of varying degrees of severity; in particular, it helps in very advanced cases. The drug contains substances that are, in fact, acaricidal agents, and the formula for their combination is very harmonious. It's all about the complexity of the composition, which was selected in such a way that the product has the greatest effect with low toxicity.
There are different forms of Dironet suitable for adult and small cats.
Let's look at the table to see what ingredients of the medicine we are talking about.
Table. Active ingredients of the drug "Dironet"
Name of active substance | Description |
Ivermectin | The essence of the work of this drug is to provide all the necessary conditions so that the drug can block all neural impulses of helminths, thereby ensuring their rapid death. 4 hours after the medicine is taken by the cat, its concentration inside the animal’s body will reach its maximum value. The substance is eliminated 24 hours after it is absorbed. The drug is effective not only against worms, but also: fleas; ixodid ticks |
Praziquantel | This drug is intended to interrupt the transport of glucose in the body of parasites, in particular to disrupt the functioning of their muscle tissue. In addition, with its help, the synthesis of adenosine triphosphoric acid is inhibited and the level of permeability of the walls of each cell increases. The peak effectiveness of the active substance after taking the drug by a cat occurs after 3 hours. After the next 24 hours, the absorbed product is completely eliminated from the body through the kidneys along with one of the biological fluids - urine |
Pirantel | The substance of the drug is characterized by long-term elimination from the animal’s intestines, which allows it to influence the worms parasitizing inside it as long as possible and as effectively as possible. Within 2 hours after taking the drug, the concentration of pyrantel reaches its maximum values. Complete elimination of this particular active substance is carried out in the body in about a day. The essence of the action of this substance is as follows: it causes severe paralysis in the worms, which ultimately leads to their death and natural removal from the cat’s body |
Dironet suspension is available with salmon flavor
The drug we are considering for cats is available in several different forms. The first and most familiar form for everyone is, of course, tablets. The standard color of this drug in the indicated form is yellow. The manufacturer claims that the medicine has the taste and aroma of meat. The product is packaged in food foil, so the packaging is considered completely safe. Each blister contains 6 tablets, each of which is divided in the middle by a deep, flat strip, which is designed to easily divide the tablets into two parts.
The second form is a suspension, which is a thick, creamy liquid, to which the manufacturer also decided to add flavor appeal by making it “salmon.” The volume of one plastic bottle is 10 milliliters. The bottle itself is made in the form of a syringe, which is very convenient, since the amount of suspension must be measured correctly so as not to harm the pet.
How to give liquid medicine to a cat?
The third form is represented by drops. This product is recommended for use in cats, since it is applied to the pet’s withers. The form of the drug is designed to destroy ecto- and endoparasites, therefore, it will be very effective for helminths. However, if your animal also has fleas or any other parasites, it is an excellent treatment for those as well.
The fourth form is also presented as a suspension, but in this case the product is intended for use by owners of small kittens. “Dironet Junior” (this is the name of the medicinal suspension for kittens) is also used in diluted form, since sometimes only with the addition of water can the desired consistency be achieved.
It is important to use the drug according to the instructions
Instructions for use and dosage
Dironet spot drops are applied to clean, undamaged skin of the cat in the withers area, after spreading the fur. The drug should be applied to places that are inaccessible for licking. After applying the product, it is not recommended to wash the animal for 4-5 days.
The dosage of the drug is calculated based on the weight of the animal. For kittens it is 0.1 ml per kilogram of animal body weight.
To kill fleas and lice eaters, the cat is treated once. For preventive purposes, the product can be used once a month during the period of parasite activity.
To get rid of ear mites, the product is used once. Repeated treatment, if necessary, is possible after a month. Before use, you should clean the ear from any dirt. If an animal is diagnosed with otitis, then Dironet is used in conjunction with antimicrobial and anti-inflammatory drugs.
For demodicosis, sarcoptic mange, and notoedrosis, the drug is used two to four times with a break of 10 days. After using the drug, it is necessary to conduct a double laboratory acarological study to confirm the positive result of treatment.
To get rid of helminths, Dironet is used once. Prevention of intestinal invasions is carried out once every three months.
Dironet tablets are taken orally. To do this, carefully grind the product and mix it into your cat’s food or treat. You can also give the drug forcibly by placing it on the root of the tongue.
One Dironet tablet is designed for 10 kilograms of animal weight. Tablets are recommended to be used for prevention once every three months, for treatment - once.
You can purchase the drug at a veterinary pharmacy. The average price for a package of the drug is from 250 rubles.
Directions for use, dosage for cats
The drug is used by animals by drip (“spot-on”) application to dry, intact skin. Before use, break off the tip of the pipette tube and, parting the fur, apply the drug to the animal’s skin along the spine, in places inaccessible for licking, in the neck area at the base of the skull or between the shoulder blades.
When treating large animals, the contents of the pipettes are applied to the skin in 3-4 places. Depending on the weight of the animal, the drug “Dironet spot-on” is used in various packaging in the doses indicated in the table. The minimum therapeutic dose of the drug for adult animals is 0.2 ml/kg of animal weight, which corresponds to 17 mg/kg of praziquantel and 4 mg/kg of ivermectin for dogs;
for cats – 17 mg/kg praziquantel and 1 mg/kg ivermectin. The minimum therapeutic dose of the drug for puppies and kittens is 0.1 ml/kg body weight, which corresponds to 8.5 mg/kg praziquantel and 2 mg/kg ivermectin for puppies, 8.5 mg/kg praziquantel and 0.5 mg/kg ivermectin for kittens. mg/kg ivermectin. Taking into account the type, age and weight of the animal being treated, a pipette tube of the required volume or a combination thereof is selected
Animal weight | Drug dose, number of pipettes | ||||||||||
Puppies from 2 months of age: | |||||||||||
up to 1 kg | 1 | ||||||||||
from 1 kg to 2 kg | 2 | ||||||||||
Adult dogs: | |||||||||||
from 2 kg to 5 kg | 1 | ||||||||||
from 5 kg to 10 kg | 2 | ||||||||||
from 10 kg to 20 kg | 3 | ||||||||||
from 20 kg to 30 kg | 4 | ||||||||||
more than 30 kg | 5 | ||||||||||
Kittens from 2 months of age: | |||||||||||
up to 1 kg | 1 | ||||||||||
Adult cats: | |||||||||||
from 2 kg to 5 kg | 1 | ||||||||||
more than 5 kg | 2 |
The drops are applied to the withers area, where the cat cannot lick them off.
Drops can be applied at any time. Their effectiveness is not affected by whether the animal has eaten or not. When using drops for the first time, if the cat is allowed to roam freely, it is necessary to leave it in the house for 3-4 hours to make sure that there is no allergy to the product.
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The drops are applied to the withers area, where the cat cannot lick them off. The wool is parted and, holding the pipette vertically, pressing lightly on it, the composition is dripped onto the skin.
Large animals weighing more than 5 kg should apply the product between the shoulder blades and along the spine, but only in those places where the pet cannot lick the composition.
Dose for cats weighing from 2 to 5 kg – 1 pipette. Large individuals require 1.5-2 pipettes. Kittens weighing less than 1 kg are given only 3 drops, and those heavier than 1 kg are given 5 drops.
A single treatment is enough to kill parasites. In order to prevent infection, preventive treatment is carried out for cats walking on the street once every 3 months; for pets that do not leave the house - once every 5 months.
Dironet spot drops are applied to clean, undamaged skin of the cat in the withers area, after spreading the fur. The drug should be applied to places that are inaccessible for licking. After applying the product, it is not recommended to wash the animal for 4-5 days.
The dosage of the drug is calculated based on the weight of the animal. For kittens it is 0.1 ml per kilogram of animal body weight.
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To kill fleas and lice eaters, the cat is treated once. For preventive purposes, the product can be used once a month during the period of parasite activity.
To get rid of ear mites, the product is used once. Repeated treatment, if necessary, is possible after a month. Before use, you should clean the ear from any dirt. If an animal is diagnosed with otitis, then Dironet is used in conjunction with antimicrobial and anti-inflammatory drugs.
For demodicosis, sarcoptic mange, and notoedrosis, the drug is used two to four times with a break of 10 days. After using the drug, it is necessary to conduct a double laboratory acarological study to confirm the positive result of treatment.
To get rid of helminths, Dironet is used once. Prevention of intestinal invasions is carried out once every three months.
Dironet tablets are taken orally. To do this, carefully grind the product and mix it into your cat’s food or treat. You can also give the drug forcibly by placing it on the root of the tongue.
One Dironet tablet is designed for 10 kilograms of animal weight. Tablets are recommended to be used for prevention once every three months, for treatment - once.
You can purchase the drug at a veterinary pharmacy. The average price for a package of the drug is from 250 rubles.
Drops are applied to the cat's skin in the withers area. To do this, the pipette is held vertically with the nose up. The tip is carefully cut off, the fur is parted in the area of the cat’s withers and drops are applied directly to the skin in several places that the cat cannot reach when licking (between the shoulder blades, on the line of the spine).
In this case, the following dosage is adhered to: if the animal weighs from 2 to 5 kg, 1 pipette is enough for it. Large cats weighing 5 kg or more are provided with 2 pipettes.
Dironet can be used to treat kittens that are already 2 months old. In this case, the dosage is followed: 3 drops for pets weighing less than 1 kg, 5 drops for babies whose weight exceeds 1 kg.
When treating the disease otodectosis, the drug is applied to the skin once. The treatment is combined with cleansing the inner surface of the ear from crusts and scabs. If there is no improvement, the procedure is repeated after 30 days.
It is recommended to carry out preventive treatments every 3-5 months.
The suspension is applied to the withers
Contraindications
To avoid negative consequences, the use of the drug is prohibited in the following cases:
- for the treatment of sick and weakened animals;
- kittens under two months old;
- pregnant females;
- when used in combination with other antiparasitic agents.
Dironet has no side effects. An exception may be cases of individual intolerance to individual components of the drug.
Very rarely, side effects may manifest themselves in the form of increased salivation, vomiting, trembling of the limbs or irritation of the skin. In this case, stop using Dironet, and the remaining product should be washed off using detergent.
Side effects
The medicine does not have a toxic effect on the cat’s body, in recommended doses it does not cause skin irritation and does not have an embryotoxic effect.
The following side effects from treatment with Dironet Spot on are rarely possible::
- increased salivation;
- lacrimation;
- skin reaction in the form of irritation, redness, rash;
- weakness;
- body trembling.
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The appearance of side effects and complications after Dironet can be caused by individual intolerance to the components of the drug or by exceeding the recommended dose. In case of unexpected effects, you should thoroughly wash the instillation site with soapy water. If allergic reactions occur, the cat may be prescribed antihistamines.
The risk of complications can be minimized by using the drug according to the instructions.
To avoid the negative consequences of Dironet Spot, it is not recommended to use it simultaneously with other anthelmintic medications.