Every spring, cats and female cats go into heat, which causes a lot of inconvenience to their owners. Animals become uncontrollable, aggressive, and lose their appetite. The only way out is to let them satisfy their need. But what to do if the birth of kittens is not part of the owner’s plans? Gestrenol, drops for cats, the instructions for which allow you to find out how to prevent unwanted pregnancy and control sexual heat, can help. The drug contains only natural hormonal components: ethinyl estadiol and propionate mepregenol, which reduce the production of its own hormones in the cat’s body and prevents ovulation.
Composition and release form of the drug
Gestrenol drops are produced in Russia, Moscow. The drug is a greenish-yellow oily liquid with a weak specific odor and taste. Gestrenol is available in plastic dropper bottles with a volume of 1, 1.5, 2, 3 or 5 ml and in tablet form. Each bottle is packed in cardboard boxes with instructions.
Gestrenol is a hormonal drug that regulates estrus in cats.
The main active ingredients of the drug:
- mepregenol propionate (1.5 mg);
- ethinyl estradiol (0.015 mg).
Various flavoring additives, sugar, soybean oil and starch are used as additional components, and to make cats more willing to take the medicine, catnip is added to it.
Release form and composition
The active component of the contraceptive for females is:
- mepregenol propionate at a dosage of 0.15 mg
- ethinyl estradiol at a dosage of 0.0015 mg
The active ingredient for males is:
- mepregenol propionate at a dosage of 0.4 mg
- ethinyl estradiol at a dosage of 0.02 mg
© shutterstock
Features of the drug
Gestrenol is one of the best contraceptives for cats. The active ingredients of the drug are synthetic hormones that inhibit ovarian function. In the process of taking it, the acidity of the vagina increases in cats, which prevents conception during mating, the estrus period is interrupted or delayed, and the cats stop producing sperm, sexual desire disappears and aggression decreases.
Important. Under no circumstances should cats be given medicine intended for cats, and vice versa.
Gestrenol is absolutely safe for animals, does not accumulate in cell tissues, and does not affect the nervous and reproductive systems of the body. The ability to fertilize and complete restoration of reproductive function appears 2-3 months after the end of taking the drug.
Dosage
The permissible dosage of the drug Gestrenol in the form of drops, calculated based on the weight of the cat.
- to complete estrus, females weighing up to 5 kg are given 4 drops at the very beginning of the heat. Course duration is 3-5 days. For larger individuals, you can increase the amount to 5-8 drops.
- 1 drop every seven days during the break between heats can stop or delay the active sexual phase.
- if there is a possibility of unnecessary fertilization - within 24 hours after sexual intercourse you need to give 2 times 8 drops. Break - 24 hours.
How to give Gestrenol to a cat can be understood from the instructions.
- To get rid of desire or complete the hunt in males weighing up to 5 kg, use 4 drops of medicine per day. Course duration is 3-5 days. It is necessary to bury at the very beginning of the hunt. Individuals weighing over 5 kg will need 4-8 drops.
- In order for the male to calm down, it is recommended to take 4 drops, regardless of weight, once every 10-15 days during the inactive period.
60 days after the end of taking Gestrenol, the renewal of the entire reproductive system of cats begins. A dose of medicine not taken on time should be given as quickly as possible. If less than half a day has passed since the last use of Gestrenol, then its effect does not decrease.
Pharmacological properties
Gestrenol is a hormonal contraceptive drug for cats. The principle of operation, which is based on the fact that mepregenol propionate (gestagen) blocks the production of follicle-stimulating and luteinizing hormones in the hypothalamus. And they, in turn, are responsible for the formation of follicles in the ovaries and ovulation.
The drug Gestrenol is safe for animals.
Ethinyl estradiol changes the composition of the cat's uterine mucus, making it viscous and thick, which prevents sperm from penetrating into the uterine cavity. And if fertilization does occur, then the fertilized egg cannot penetrate the endometrium and an involuntary termination of pregnancy occurs. In cats, the active ingredients of the drug reduce sperm activity.
Gestrenol drops are absolutely safe for the health of the animal, and the active components are completely eliminated from the body along with urine within two days.
Indications for use
Gestrenol affects not only the physiological processes in the cat’s body, but also the animal’s behavior. Drops allow you to adjust the period of estrus (interrupt or delay) and reduce the production of sex hormones.
Purpose of the drug:
- decreased libido;
- termination of an unplanned pregnancy;
- correction of the appearance of estrus;
- reduction of aggressiveness and agitation.
Before using the drug, the instructions for use should be carefully studied to avoid unpleasant consequences in the future.
Instructions for use and dosage for cats
Before use, the bottle with the drug must be shaken well. Drops can be administered directly into the animal's mouth, added to food, or dripped onto the nose. So, how many times a day should I spray the drug? Gestrenol is most effective at the very beginning of the estrus period.
The drug is given to cats in the dosage specified in the instructions.
To interrupt it, it is enough to give 4 drops of the drug once a day to cats weighing less than 5 kg. For animals weighing 6-10 kg, the single daily dose is increased to 5-8 drops. The course of treatment is at least 3-5 days. It is impossible to interrupt treatment and then resume it again. Even after sexual heat has passed, the medicine is given for another day.
If an unplanned, accidental mating occurs, then, as protection against pregnancy, the cat is given 8 drops of the drug at a time. In this case, the dosage is standard, regardless of weight and age. A day later, another 8 drops of Gestrenol are given.
To delay the onset of the next estrus, you can give the drug as a prophylaxis during sexual rest. The dosage will be 4 drops once a week. But you shouldn’t interrupt estrus more than twice a year. This may harm the animal.
Important. To prevent pregnancy successfully, the drug must be given to the animal within 24 hours after mating.
Instructions for use
Gestrenol is sold in veterinary pharmacies and contains detailed instructions. However, it is not recommended to use it without a veterinarian's prescription. Your cat may have had hormonal imbalances before puberty.
Reviews from veterinarians insist that the systematic use of such drugs provokes irreversible changes in the reproductive system in cats, including malignant neoplasms.
Therefore, it is better to use Gestrenol as a temporary measure, and eventually castrate or neuter the pet.
When to give?
Gestrenol is given to cats for:
- reducing the degree of desire;
- complete cessation of hunting;
- calm.
In cats, Gestrenol is used if necessary:
- stop estrus;
- prevent pregnancy;
- calm down;
- delay the onset of estrus.
Attention! The use of the drug is not effective if more than 2 days have passed since the start of sexual heat.
Dosage
The dosage depends on the form of release, in addition, the weight of the cat plays an important role.
Gestrenol drops for cats are used depending on the desired result. In this case, treats are soaked in the medicine or dripped directly into the mouth or nose so that the animal licks:
- To stop estrus, cats up to 5 kg need 4 drops at the first sign of heat. Course – 3-5 days. For larger animals, the dosage is increased to 5-8 drops;
- 1 drop per week during the period between estrus will help calm or delay the onset of estrus;
- to prevent the risk of unwanted pregnancy, no later than a day after mating, give 8 drops twice. The interval between doses is 24 hours.
Drops for cats are used in the same way according to the instructions:
- 4 drops of Gestrenol per day will help reduce the degree of attraction or stop hunting in cats up to 5 kg. Course – 3-5 days. They begin to drip at the first sign of concern. Moreover, for cats over 5 kg, the dosage is 4-8 drops;
- To calm a cat, it is enough to give 4 drops, regardless of weight, every 10-14 days during periods of calm.
The tablets are given according to the instructions. The recommended dosage is 1-2 pieces for 3-5 days from the onset of sexual desire. At the same time, young cats are given 2 pieces at a time on the first day.
To prevent estrus and calm your pet, give one tablet once a week after the cessation of hunting.
Pregnancy can be prevented by giving 2 tablets no later than 24 hours after unwanted mating. Repeat after 24 hours.
Contraindications and side effects
Like any medicine (even the safest), Gestrenol drops also have a number of contraindications. The drug should not be given to young, immature kittens or cats during pregnancy and lactation. Gestrenol is contraindicated in animals suffering from diabetes, genitourinary diseases, and cancer. Sometimes a pet may develop individual intolerance to certain components of the drug. In this case, the veterinarian may advise changing the contraceptive.
If you greatly exceed the required dosage, the following side effects may occur:
- changes in behavior;
- vomit;
- increased appetite;
- allergic dermatitis;
- profuse salivation.
If the instructions are strictly followed, Gestrenol does not cause side effects or addiction. It is compatible with most medications.
Recommendations for use and storage conditions
There are no special precautions when working with the drug; it belongs to the group of low-toxic drugs. Store Gestrenol in a dry, dark place, out of reach of children and pets, away from direct sunlight. Place it separately from food products and household chemicals, with a storage temperature of 0 to +25C. Sometimes short-term freezing of the drug is allowed. The shelf life is 3 years, after which the medicine cannot be used.
Gestrenol is stored in a dry and dark room at above-zero temperatures.
Contraceptive GESTRENOL DROPS for cats 1.5 ml 1/20 Astrapharm
The price is valid only when placing an order in the online store.
Product availability in the ZooPark retail chain as of: 03/11/2021 18:15:00
Warehouse - YES Novokuibyshevsk - YES TC Ladya - YES TD Zakhar - YES TC Samolet - YES TC Megacity - YES Chernorechenskaya 38 - YES 9-Proseka - YES Revolutionary 137 - YES Michurina 138 - YES Sadovaya 239 - YES Shvernika 19a - YES
Gestrenol drops for cats with catnip, fl. 1.5 ml
COMPOSITION AND FORM OF RELEASE
The hormonal contraceptive Gestrenol in 1 bottle contains 1.5 mg of mepregenol propionate and 0.015 mg of ethinyl estadiol, a flavoring agent and auxiliary components as active ingredients. In appearance it is an oil solution from yellow to yellow-green color with a weak specific odor. 1.5 ml are packaged in polymer dropper bottles, which are packed in cardboard boxes.
PHARMACOLOGICAL PROPERTIES
Mepregenol propionate, which is part of the drug, is a synthetic derivative of the hormone progesterone and has the property of inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are produced by the anterior pituitary gland. When using the drug before the onset of estrus (estrus), the synthesis of estrogen by the ovarian follicles is inhibited, which prevents the development of morphological and psychophysiological changes in females associated with the sexual cycle. In addition, if there is insufficient LH, the ovulation process becomes impossible. Ethinyl estadiol changes the acidity of vaginal mucus in females, making it more viscous, which interferes with the progress of sperm and causes their death. In addition, once fertilization occurs, the hormone prevents implantation of the fertilized egg into the endometrial wall and the pregnancy is terminated. Biotransformation and primary metabolism of the drug occurs in the liver and is excreted from the body in the form of salts within 2 days. In terms of the degree of impact on the body of warm-blooded animals, the drug is classified as a low-hazard substance and in recommended doses does not have a resorptive-toxic, mutagenic or sensitizing effect.
INDICATIONS
Prescribed to cats to protect against unwanted pregnancy, to reduce sexual activity and correct psychophysiological changes during the period of sexual heat.
DOSES AND METHOD OF APPLICATION
The drug is given orally to animals individually by applying a calculated number of drops into the mouth, nose or treat in the doses indicated in the table:
| Purpose of using the drug | Animal weight, kg | Number of drops of the drug |
| Interruption of estrus (estrus) | up to 5 | 4 |
| 6 10 | 5 8 | |
| Protection from unwanted pregnancy after accidental mating | Regardless of the animal's body weight | 8 |
| During the period of sexual rest for preventive purposes, delaying the onset of estrus | Regardless of the animal's body weight | 4 |
Before use, the bottle of solution should be shaken thoroughly. The drug is administered daily for 3-5 days from the moment the first signs of heat appear. The contraceptive effect is reduced if the animal has not received the drug for more than 2 days from the start of estrus. In order to increase efficiency, after eliminating the signs of sexual arousal, the drug should be continued for another day; in some cases, as directed by the veterinarian, the course is extended until sexual estrus completely ceases. It is not advisable to interrupt estrus more than twice a year. After an accidental, unwanted mating, the cat is given Gestrenol drops no later than 24 hours after mating, twice at intervals of a day. During the period of sexual rest, for the preventive purpose of stabilizing excessive sexual arousal, accompanied by aggression, vocalization and other individual behavioral manifestations of sexual desire, as well as delaying the onset of estrus, Gestrenol drops are given once a week, but not more than 18 months in a row. Reproductive function in cats is restored 2-3 months after the last use of a contraceptive.
SIDE EFFECTS
In rare cases, with increased individual sensitivity to the components of the drug, or an overdose, the animal may experience vomiting, excessive salivation, increased appetite, allergic reactions on the skin, and changes in behavior. If these signs appear, use of the drug should be discontinued.
CONTRAINDICATIONS
Individual hypersensitivity to the components of the drug. Young cats before puberty cannot be treated. The drug is not intended for use in cats. It is not recommended to prescribe it to cats suffering from urolithiasis, diabetes mellitus and tumoral mammary hyperplasia.
SPECIAL INSTRUCTIONS
No special precautions are required.
STORAGE CONDITIONS
In a dry place, protected from direct sunlight and out of reach of children and animals, away from food and feed at a temperature of 0 to 25 °C. During transportation, short-term freezing of the drug is allowed. Shelf life: 3 years.
Reviews from veterinarians
Elena Ivanovna, veterinarian. When cat owners come to me with a question about how best to help their pet during sexual heat without resorting to sterilization or castration, I always recommend Gestrenol drops. This is one of the safest and most effective contraceptives. Despite the low cost, the drug is of very high quality and works better than expensive analogues.
Irina, veterinarian. In my opinion, Gestrenol drops are the best drug of this type. Thanks to its consistency, it is easy to use, effective, and does not cause addiction or side effects. The animal's sexual function is fully restored within 2-3 months after the end of administration. But we must remember that as a preventative measure, you should not give the drug to a cat for more than one and a half years in a row.
