general description
Stomorgyl is a combination drug that contains two components as an active ingredient: spiramycin and metronidazole. Thanks to this, the medicine has a wide spectrum of action.
Composition and action
Spiramycin is a natural antibiotic, the effect of which is that it prevents the proliferation of bacterial cells, which leads to their death. The substance is effective against:
- staphylococci;
- streptococci;
- listeria;
- clostridium;
- chlamydia;
- other pathogenic microorganisms.
The antibiotic belongs to the group of macrolides and is considered one of the safest antibacterial drugs. The maximum concentration of spiramycin is achieved 4-8 hours after taking the medicine.
The second active component of the drug is metronidazole. It is an antiprotozoal agent that is effective against protozoan microorganisms. It begins to act within 1-1.5 hours after taking the antibiotic, actively destroying harmful organisms:
- amoeba;
- Giardia;
- Trichomonas;
- clostridia;
- Helicobacter pylori.
The medicine is available in the form of tablets, different types have different concentrations of active ingredients, designed for dogs of different breeds:
- small – 150,000 IU (international units) of spiramycin, 25 mg of metronidazole;
- medium - 750,000 IU and 125 mg - respectively;
- large – 1,500,000 IU and 50 mg.
This allows you to choose the right dose and avoid overdose.
Composition, release form and storage conditions
Stomorgyl belongs to the group of antibacterial combination medications. It contains 2 active components: spiramycin and metronidazole. The first substance is a macrolide antibiotic, effective against a wide range of gram-positive microorganisms and some gram-negative bacteria. The second component, metronidazole, has an antiprotozoal effect and is active against protozoa and anaerobic pathogens.
Stomorgyl is used for bacterial infections in cats
Additionally, the drug contains:
- sorbitol;
- magnesium stearate;
- aluminum hydroxide;
- white dextrin;
- starch;
- gelatin.
The drug is available in yellow tablets, convenient for oral administration. The medication should be stored for no more than three years, and the room temperature should not exceed 25 degrees.
This drug is considered a moderately hazardous substance. It does not have a negative effect on the fetus and does not provoke the development of a severe allergic reaction.
Stomorgil 2
This type of medicine has the lowest dosages of active ingredients:
- spiramycin - 150,000 IU;
- metronidazole - 25 mg.
It is mainly used to treat animals whose body weight starts from 2 kg. This is relevant when treating growing and small cats.
Stomorgyl 2 is used to treat small animals
Stomorgil 10
The drug, numbered 10, contains slightly more active ingredients in 1 tablet:
- spiramycin - 750,000 IU;
- metronidazole - 125 mg.
This medication is prescribed for the treatment of animals whose body weight exceeds 10 kg. This product is suitable for medium and large, as well as well-fed cats.
Stomorgyl 10 is often prescribed for the treatment of medium and large animals
Stomorgil 20
This medication contains the largest number of active ingredients in 1 tablet:
- spiramycin - 1,500,000 IU;
- metronidazole - 250 mg.
This type of drug is most often prescribed for the treatment of large breeds of cats and dogs, whose weight starts from 20 kg.
Stomorgyl 20 is used to treat large animals, from 20 kg and more
Dosage
The treatment regimen is determined by the veterinarian after examining the animal, test results and clarifying the diagnosis. A convenient dosage form allows you to determine the required amount of active substance depending on the weight of the animal:
- Stomorgil-2 is intended for small breed dogs, 1 table. /2 kg of animal weight;
- Stomorgyl-10 – 1 tablet/10 kg body weight, which is convenient for medium breed dogs;
- Stomorgil-20 - designed for large individuals, the dose is 1 tablet / 20 kg of weight.
The daily dose is 1 tablet; it is better to give the medicine with food or forcefully - on the root of the tongue. Having closed the dog's mouth, you need to lightly stroke the throat, this will cause a swallowing reflex.
The duration of therapy depends on the disease, the characteristics of the disease course and the presence of complications. The treatment plan is drawn up by a veterinarian. Typically, the course of antibiotic treatment is 5-10 days. Less than 5 days - treatment may be ineffective, since infectious agents are quite tenacious and able to adapt to changed conditions.
Indications for use
Stomorgyl is prescribed to dogs as part of complex therapy for diseases of the oral cavity:
- with gingivitis;
- with stomatitis;
- with periodontitis;
- with pyorrhea, etc.
It can also be used in the treatment of diseases caused by bacteria, protozoa and fungi that are sensitive to spiramycin and metronidazole. Usually the drug is prescribed for acute or subacute course of the pathology.
According to the classification according to GOST 1976, the drug is classified as a moderately hazardous substance. If the recommended dose is not exceeded, it is not addictive and does not have a toxic effect on the development of the embryo, but before use, consultation with a veterinarian is necessary.
The dosage of the drug is calculated taking into account the concentration of active components and the weight of the animal. Please note the following:
- 1 tablet of Stomorgil 2 is designed for 2 kg of weight;
- 1 tablet of Stomorgil 10 – per 10 kg;
- 1 tablet of Stomorgil 20, respectively, per 20 kg.
The medicine should be taken once a day. Tablets can be given hidden in the food. For these purposes, it is better to choose the animal’s favorite treat. Although there is a high probability that the pet will refuse the “treat”, so the medicine will have to be given forcibly. You can do it like this:
- Open the animal's mouth.
- Place a tablet on the root of your tongue.
- Close your mouth but keep your head up.
- Stroke the neck to encourage swallowing movements.
It is not recommended to crush the tablets and add them in powder form to the animal’s food. Due to the strong bitter taste, the dog will refuse the offered treat, and if it eats it, it will salivate heavily. Tablets can only be divided according to the notches provided by the manufacturer.
The course of treatment lasts from 5 to 10 days, depending on the complexity and stage of the disease, and the characteristics of its course. The duration of treatment and dose should be determined by the doctor. It is not recommended to take the medicine for less than 5 days, since bacteria can survive and adapt to new conditions. Taking the medicine in this case will be useless.
It is advisable not to miss taking the drug on time, as this may lead to decreased effectiveness. If this does happen, you can take the medicine as soon as possible at the prescribed dose, and then return to the previously used treatment regimen.
Features of application
It is necessary to take antibiotics at regular intervals, at the same time every day. Skipping a dose will negatively affect the effectiveness of treatment. If you fail to give the pill on time, you need to try to do it as soon as possible, and then return to your previous dosing schedule.
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If it is necessary to use an antibiotic to treat pregnant and lactating females, the veterinarian must assess the risks for the offspring and the dog itself, only after which a choice is made in favor of one drug or another. The same applies to the treatment of animals with chronic pathologies of the kidneys, heart, and liver. In this case, therapy is carried out under the supervision of a veterinarian.
Antibiotics should not be given:
- simultaneously with other antibacterial drugs of the macrolide group;
- with medications containing alcohol.
Instructions for use
It should only be taken orally (by mouth). Stomorgyl 2, 10, 20 is given to pets of all breeds exclusively individually once a day in the following dosage: 75,000 IU of spiramycin and 12.5 mg of metronidazole per 1 kg, from the proposed recommended calculation:
- 1 capsule of Stomorgil 2 – per 2 kg of dog’s weight.
- 1 unit of Stomorgil 10 - 10 kg of dog weight.
- 1 capsule of Stomorgil 20 - 20 kg of animal weight.
The course of treatment should be continued while paying attention to the general health of the animal. Usually it is approximately 5-10 days from the date of taking the first tablet. It is important to consult with your veterinarian before starting treatment with this drug.
Tablets cannot be given to an animal in crushed form: it is only permissible to divide the tablet into several shares, based on the boundaries of the dividing line on it.
If the next dose was ignored for any reason, then the course of treatment should be resumed as soon as possible according to the same principle and regimen.
Acceptance is allowed for bitches expecting offspring, as well as for breastfeeding individuals.
It should be stored in a completely closed box, separate from food on a dry and dark shelf at a temperature of 1 to 25 degrees Celsius. Its shelf life is exactly three years. It must be stored only in a closet inaccessible to children.
Restrictions
An antibacterial agent is not prescribed:
- with individual intolerance;
- at an early age for puppies - up to 2 months;
- during periods of pregnancy and lactation.
With increased sensitivity, itching, redness of the skin, and impaired digestive function may occur. Such symptoms should be reported to your veterinarian, who will prescribe antihistamines and symptomatic therapy.
In case of an overdose, the animal may experience the following symptoms:
- stomach upset;
- nausea, vomiting;
- increased salivation;
- lethargy, depressed state.
Such signs require an immediate visit to the veterinary clinic, where the pet’s stomach will be rinsed and symptomatic treatment will be prescribed.
Stomorgil, 2, up. 20 tablets
COMPOSITION AND RELEASE FORM Stomorgil contains spiramycin and metronidazole as active ingredients, as well as auxiliary components: aluminum hydroxide, sorbitol, white dextrin and magnesium stearate. One tablet of Stomorgyl 2 contains 150,000 IU of spiramycin and 25 mg of metronidazole, Stomorgyl 10 - 750,000 IU of spiramycin and 125 mg of metronidazole, Stomorgyl 20 - 1,500,000 IU of spiramycin and 250 mg of metronidazole. In appearance it is a yellow tablet. 10 tablets are packaged in laminated paper blisters, 2 pieces (Stomorgyl 2 and Stomorgyl 10) and 1 piece (Stomorgyl 20) in a cardboard box. PHARMACOLOGICAL PROPERTIES The active components of the drug - metronidazole and spiramycin - exhibit synergistic action against a wide range of pathogenic microorganisms, including protozoa. Spiramycin, as a natural antibiotic from the group of macrolides, is capable of reversibly binding to ribosomes and suppressing protein synthesis in the microbial cell. Active against Streptococcus spp. (including Streptococcus pneumoniae), Staphylococcus aureus, Meningococcus spp., Bordetella spp., Corynebacterium spp., Listeria monocytogenes, Clostridium spp., Mycoplasma mycoides, Chlamydia spp., Leptospira interrogans, Campylobacter spp., Haemophilus spp., Bacteroides nodosus, Fusobacterium spp. and protozoa: Toxoplasma gondii. Metronidazole disrupts the respiratory processes in the cell, which causes the death of pathogenic protozoa. In addition, in some species of anaerobes it has the ability to suppress DNA synthesis and cause its destruction. Active against gram-positive anaerobes: Clostridium spp., Eubacterium spp., Helicobacter pylori and gram-negative bacteroids and fusobacteria, as well as the protozoa Trichomonas. When administered orally, the drug is well absorbed from the gastrointestinal tract (bioavailability is about 100%) and the maximum concentration of its components in the blood is observed after 1.5-3 hours. In terms of the degree of impact on the body of warm-blooded animals, the drug is classified as a low-hazard substance and in recommended doses does not have a resorptive-toxic, mutagenic or sensitizing effect. INDICATIONS Prescribed to dogs and cats for the treatment of infections caused by microorganisms sensitive to spiramycin and metronidazole, especially in the acute and subacute period of the disease. In the complex therapy of inflammatory diseases of the oral cavity, including stomatitis, gingivitis, pyorrhea and periodontitis. DOSES AND METHOD OF ADMINISTRATION Stomorgyl tablets are administered orally to animals once a day at the rate of 75,000 IU of spiramycin and 12.5 mg of metronidazole per 1 kg of animal weight, which corresponds to one Stomorgyl 2 tablet per 2 kg of animal weight, one Stomorgyl 10 tablet per 10 kg of animal weight animal and one tablet of Stomorgyl 20 per 20 kg of animal weight. The duration of the course of treatment is 5-10 days, depending on the individual characteristics of the body and the nature of the disease. SIDE EFFECTS In very rare cases, with increased individual sensitivity to the components of the drug, the animal may experience allergic reactions and vomiting. If these signs appear, use of the drug should be discontinued. CONTRAINDICATIONS Increased individual sensitivity to the components of the drug. It is not recommended to use crushed tablets, or to prescribe them with other antibiotics from the macrolide group. SPECIAL INSTRUCTIONS No special precautions are provided. The drug is approved for use in pregnant and lactating females. STORAGE CONDITIONS: In a dry place, protected from light and out of reach of children and animals, at a temperature of 5 to 25 °C. Shelf life: 3 years.