General information about the drug
Trade name of the drug: Drontal plus. International nonproprietary name: pyrantel, praziquantel, febantel.
Dosage form: tablets for oral use per 10 kg of dog weight and per 35 kg of dog weight.
The drug contains as active ingredients:
- In 1 tablet per 10 kg: pyrantel embonate - 144 mg, praziquantel - 50 mg and febantel - 150 mg,
- In 1 tablet per 35 kg: pyrantel embonate - 504 mg, praziquantel - 175 mg and febantel - 525 mg,
- Excipients: lactose monohydrate, microcrystalline cellulose, corn starch, polyvidone, magnesium stearate, sodium lauryl sulfate, colloidal anhydrous silicon, food additive with meat flavor.
In appearance, the drug (1 tablet per 10 kg) is a bone-shaped tablet from light brown to dark brown in color with a dividing groove in the center. In appearance, the drug (1 tablet per 35 kg) is an oval-shaped tablet from light brown to dark brown in color with a dividing groove in the center.
The shelf life of the drug, subject to storage conditions, is 5 years from the date of production. Do not use the drug after the expiration date.
The tablets are packaged in blisters of 2 and 6 tablets, which are packaged in cardboard boxes along with instructions for use.
Store the drug in the manufacturer's sealed packaging in a dry place, protected from direct sunlight, away from food and feed, at a temperature of 0°C to 25°C in places inaccessible to children. Unused medicinal product is disposed of in accordance with legal requirements.
Available without a veterinarian's prescription.
Composition and pharmacological properties
The high effectiveness of the drug is due to the content of three active components:
- febantel;
- pyrantel;
- Praziquantel
The first two substances complement each other and act on large helminths, as well as Giardia - protozoan microorganisms. Praziquantel is aimed at killing tapeworms. The auxiliary components are lactose, corn starch, and a natural meat-flavored additive.
Biological properties
"Drontal" for dogs is a combined broad-spectrum anthelmintic drug. Destroys tape and roundworms.
The main active ingredients are absorbed into the intestinal walls, then enter the blood. They are eliminated naturally after a maximum of two days.
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"Drontal Plus" is a low-hazard substance. This drug is characterized by the manufacturers as:
- safe;
- effective;
- easy to use.
The active ingredients are absorbed by helminths through the skin, and this leads to their paralysis. "Drontal Plus" is destructive not only for adult individuals, but also for other stages of helminth development.
Release form
Drontal-plus is available only in tablet form. There are two versions of the drug:
- for puppies and dogs of small and medium breeds (from 2 to 20 kg);
- for medium and large breeds (from 20 kg and more).
Each tablet is contained in a sealed blister made of aluminum foil. The package contains stickers designed to be recorded in your pet’s passport - this allows you to remember the date of the animal’s scheduled deworming.
Drontal For dogs plus meat flavor
Dosage form: tablets for oral use per 10 kg of dog weight and per 35 kg of dog weight. Drontal Plus contains as active ingredients:
- in 1 tablet per 10 kg : pyrantel embonate - 144 mg, praziquantel - 50 mg and febantel - 150 mg,
- in 1 tablet per 35 kg : pyrantel embonate - 504 mg, praziquantel - 175 mg and febantel - 525 mg,
- as well as excipients: lactose monohydrate, microcrystalline cellulose, corn starch, polyvidone, magnesium stearate, sodium lauryl sulfate, colloidal anhydrous silicon, food additive with meat flavor.
In appearance, Drontal Plus (1 tablet per 10 kg) is a bone-shaped tablet from light brown to dark brown in color with a dividing groove in the center. In appearance, Drontal Plus (1 tablet per 35 kg) is an oval-shaped tablet from light brown to dark brown in color with a dividing groove in the center.
The shelf life of the drug, subject to storage conditions, is 5 years from the date of production. Do not use Drontal Plus after the expiration date.
Drontal plus tablets are packaged in blisters of 2 and 6 tablets, which are packaged in cardboard boxes along with instructions for use.
Store the drug in the manufacturer's sealed packaging in a dry place, protected from direct sunlight, away from food and feed, at a temperature of 0°C to 25°C in places inaccessible to children. Unused medicinal product is disposed of in accordance with legal requirements. Available without a veterinarian's prescription.
Drontal plus is prescribed to dogs for preventive and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, hookworm, trichuriasis) and cestodiasis (tenidosis, dipylidiasis, echinococcosis, mesocestoidosis) and giardiasis (giardiasis).
A contraindication to the use of the drug is the animal’s individual hypersensitivity to its components (including a history of it).
The drug is administered to dogs individually once at the rate of 1 bone-shaped tablet per 10 kg of animal weight or 1 oval-shaped tablet per 35 kg of animal weight. The dosages of the drug are indicated in the table:
Dog weight | Dosage of the drug Drontal plus (1 tablet per 10 kg) |
Puppies and small breed dogs | |
2-5 kg | 1/2 tablet |
6-10 kg | 1 tablet |
Medium breed dogs | |
11-20 kg | 2 tablets |
21-30 kg | 3 tablets |
Large breed dogs | |
31-40 kg | 4 tablets |
41-50 kg | 5 tablets |
For dogs weighing more than 50 kg, a dosage of 1 tablet per 10 kg of animal weight is used.
Dog weight | Dosage of Drontal plus (1 tablet per 35 kg) |
10-17.5 kg | 1/2 tablet |
17.5-35 kg | 1 tablet |
35-52.5 kg | 1 1/2 tablets |
52.5-70 kg | 2 tablets |
For dogs weighing more than 70 kg, a dosage of 1 tablet per 35 kg of animal weight is used.
Thanks to the flavoring additive, the drug is easily eaten by dogs.
For therapeutic purposes, animals are dewormed according to indications, for preventive purposes - quarterly in a therapeutic dose. A preliminary starvation diet and the use of laxatives before deworming are not required.
When treating giardiasis, the drug is used in recommended dosages for 3 days in a row.
When deworming dogs, it is recommended to carry out disinfection and disinfestation of places where animals are kept in order to avoid re-infection.
Symptoms that occur during an overdose of the drug have not been established. No specific effects of the drug upon first administration or upon its discontinuation have been identified.
Drontal Plus should not be used in pregnant bitches during the first two thirds of pregnancy. The drug is approved for use during lactation. It is not recommended to use Drontal Plus on puppies younger than 2 weeks of age and weighing less than 2 kg.
In case of non-compliance with the established period of repeated treatments, the use of the drug should be resumed in the same dosage according to the same scheme.
As a rule, there are no side effects or complications when using the drug Drontal plus in accordance with these instructions. If the individual sensitivity of the animal to the components of the drug is increased, increased salivation, diarrhea or vomiting are possible. These symptoms are short-lived, disappear spontaneously and do not require the use of medications.
It is not recommended to use Drontal plus with drugs containing piperazine due to possible antagonistic effects.
Drontal Plus is not intended for use in productive animals.
When working with the drug, you should follow the general rules of personal hygiene and safety precautions provided for when working with medicines. When finished, wash your hands with warm water and soap. While working with the drug, smoking, drinking and eating are not allowed. In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water. People with hypersensitivity to the components of the drug should avoid direct contact with Drontal Plus. If allergic reactions occur or if the drug accidentally enters the human body, you should immediately contact a medical facility (bring with you the instructions for use of the drug or the label).
How the drug works
Drontal is a combination anthelmintic medicine. Pyrantel in combination with febantel enters the body of the parasite, disrupting the process of its muscle innervation and transport of substances, which leads to paralysis and subsequent death. Praziquantel works on a similar principle, but only affects tapeworms.
Drontal Plus is quickly absorbed in the dog's intestines and excreted from the body in the urine. The action of the product is low-toxic (hazard class 4 according to GOST).
Pharmacodynamics and pharmacokinetics
The medication has a combined effect. It is effective in ridding your dog of roundworms. The drug also acts on tape parasites. Drontal plus is effective in the fight against Giardia that lives in the pet’s body.
Febantel leads to paralysis of the helminth. This active substance disrupts the supply of glucose to the helminth's body, which leads to its death. Pyrantel embonate also provokes the development of paralysis. Febantel along with pyrantel embonate are excreted from the dog's body in feces over a period of 24 to 48 hours.
Praziquantel quickly enters the helminth's body through its membranes. A component of the drug disrupts the absorption of glucose, provokes disruptions in metabolic processes and affects nerve endings. Against this background, the parasite experiences paralysis, ending in its death. Praziquantel is eliminated from the pet's body primarily through urine.
Drontal for dogs is not a toxic drug. Its negative impact on the animal’s body is minimal. The medication is successfully tolerated by both puppies and adults. Drontal tablets do not cause allergic reactions in dogs.
How it works
The medicine has a wide spectrum of action. It is effective against various types of round and tapeworms, Giardia. This efficiency is achieved by combining three components:
- Praziquantel
has a detrimental effect on cestodes. It disrupts metabolic processes, in particular the absorption of glucose necessary for life, and affects the functioning of the nervous system. As a result, paralysis occurs, and then the death of the parasites. - Febantel
has a similar effect, as it also complicates the transport of glucose. In addition, the substance increases the permeability of cell membranes, which leads to muscle spasms and paralysis, and after inevitable death. - Pyrantel embonate
acts against nematodes. Increased permeability of their cells leads to rapid death. In addition, the substance promotes the release of parasites from the animal’s body naturally (along with feces).
All components are quickly absorbed in the intestine and are excreted after a while along with feces and urine. If you follow the recommended doses, the drug is safe because it does not cause embryotoxic or mutagenic effects. It is not addictive and can be used for pets of different breeds and ages.
Indications for dogs
Symptoms of worm infection will not take long to appear. Just watch your pet and you will find:
- appearance has changed;
- lethargy and inactivity appeared;
- an unnatural whiteness of the mucous membranes is noticeable in the mouth;
- the fur stopped shining, became ruffled, and dandruff appeared;
- the animal often swears, sometimes vomits;
- the dog is losing weight, while eating a lot;
- chews on inedible objects;
- mucus, larvae and parasites are visually observed in feces.
- “rides the butt” in order to scratch the anus.
- rickets appeared.
A dog can die from infestation with worms.
Use of the drug
The instructions for Drontal Plus for dogs are simple. The drug is given to animals as a preventive measure (can be prescribed as a therapeutic measure) against mixed helminthiasis. Wide range of effects that the drug has.
Treats helminthiasis caused by:
- Nematodes (hookworms or toxocariasis);
- Cestodes (dipylidiasis, echinocococosis, taeniasis).
Helminths actively absorb the enzymes of the drug, which, when they enter the body of the parasite, either kill it or completely paralyze its nervous system and immobilize it. Then the drug, together with the helminth, naturally leaves the animal’s body.
Instructions for use
Drontal is intended for oral administration.
It is better to give the medicine to dogs at the time of morning feeding. If the animal is already accustomed to tolerate pill therapy and can eat it on its own, then feel free to give it to the dog without using “tricks.” Dogs rarely take any medication calmly and refuse to swallow the pill on their own. Drontal does not enter into chemical reactions with foreign molecules and compounds, so it can be added to food, wrapped in a meat product and fed to an animal.
It retains its properties when crushed, so it can be crumbled or grated, and the resulting powder can simply be sprinkled on the animal’s food.
There is no need to keep the dog on a starvation diet after or before introducing the drug into the body. There is absolutely no need to combine Drontal with laxatives.
The drug is contraindicated for:
- Dogs that have suffered illness or are weakened for other reasons.
- Sick animals.
- Dogs in a state of pregnancy, in the first 2/3 of the period.
Instructions for use Drontal plus for dogs
In the packaging of the drug Drontal Plus for dogs, instructions for use are present in the form of an insert, but dog owners often do not buy the whole package, so how to give Drontal deworming tablets for dogs has to be searched on the Internet. It is for such cases that the Dai Paw website has rewritten the instructions for using the drug and shared it below.
Indications for use of Drontal plus
Veterinarians recommend the use of Drontal for dogs not only for removing worms, but also for preventive purposes. This is exactly what the drug is intended for. It is effective against nematodes (toxascariasis, hookworm, toxocariasis, uncinariasis, trichocephalosis) and cestodoses (dipilidiosis, taeniasis, diphyllobothriasis, echinococcosis, mesocestoidosis). Since Dontal Plus has a wide spectrum of action, it can be used independently (if you identify symptoms of worms in your dog).
How to use Drontal for dogs
On the package insert for Drontal Plus for dogs, the instructions read: tablets are administered once when feeding the animal, the dosage is calculated using the formula 1 tablet per 10 kilograms of dog weight. Since there is Drontal for dogs with the taste of meat, when mixed into meat, the dog will not detect the tablets and will eat it. In order not to calculate the dosage yourself, you can look at it in the table we have compiled.
Animal weight | Dosage for puppies and small dogs |
from 0.5 to 1.9 kg | 1\4 tablets (quarter tablet) |
from 2 to 5 kg | 1\2 tablets (half tablet) |
from 6 to 10 kg | 1 tablet |
Dosage for medium and large dogs | |
from 11 to 20 kg | 2 tablets |
from 21 to 30 kg | 3 tablets |
from 31 to 40 kg | 4 tablets |
from 41 to 50 kg | 5 tablets |
If the dog refuses to eat food with a mixed deworming agent, the drug should be forcibly administered - in the form of an aqueous suspension or tablets should be placed on the root of the tongue. The suspension is prepared at the rate of 1 crushed tablet per 10 ml; this mixture is administered to the animal using a syringe without a needle.
The use of Drontal Plus for dogs does not require any prior fasting diet or prior use of laxatives. In order to prevent helminths, the anthelmintic drug Drontal Plus is given to the dog four times a year, in the dosage indicated above.
Prevention
Considering that it is impossible to completely expel worms from a dog’s body, prevention is also treatment. Veterinarians recommend deworming 4 times a year, every 3 months. Puppies are sanitized from the age of two weeks, and “Drontal Plus for puppies” is produced for them. It is advisable, and if the owner is seriously concerned about the health of the pet, then after removing the worms, vaccination must be done. She consolidates the result.
Important! An accurate test for any type of worms and parasites is an enzyme-linked immunosorbent test; it gives a 90% correct result.
Helminths are divided by type and by their location in the body.
- Intestinal worms are the most common. They are the ones that cause weight loss and indigestion. They are dangerous because they clump into balls in the small intestine, causing obstruction. The animal usually dies.
- Lungworms . Symptoms of their presence are coughing and frequent pneumonia in dogs. They cannot be detected without special laboratory tests.
- Heartworms . Dogs become infected with this type of parasite through blood-sucking insects. Symptoms are similar to heart ailments: shortness of breath, drowsiness, increased fatigue. Often lead to sudden death of the dog from a heart attack.
Safety precautions and hygiene rules
Almost all worms observed in dogs are transmitted to humans, especially children. Parents try to limit their child’s contact with animals precisely for this reason.
Mandatory hand washing with soap after every interaction with a pet does not always save the situation. It is difficult to give advice in this situation; everyone decides for themselves what to do.
Important! Drontal is not used if therapy with piperazine is prescribed.
When working with Drontal Plus, as with any other chemical, precautions are necessary, especially for allergy sufferers. In order to avoid troubles, do not allow the drug to come into contact with the skin. If the drug gets into your eyes, you must rinse them with plenty of water. If an allergic reaction occurs, you need to go to the hospital.
Did you know? A dog spreads worm eggs up to 5 meters through its breath, a cat spreads it up to 3 meters.
Drontal plus tablets for dogs
The drug Drontal plus for dogs is intended for the prevention and removal of worms. Available in the form of tablets that are effective against the most common helminths - nematodes and cestodes (roundworms and tapeworms, respectively) at all stages of their development.
Active substances
Drontal plus anti-worm tablets are pale yellow in color, there are 6 of them in one package. Each tablet weighing 0.66 grams contains filler and the following active ingredients:
- praziquantel - 50 mg;
- pyrantel embonate - 144 mg;
- febantel - 150 mg.
Analogues of the drug
Drontal Plus can be replaced with one of the drugs indicated in the table. They have the same effect, and the composition and release forms are synonymous with the medication in question or differ slightly.
Name What is the difference Average price
Kaniverm | Contains the same active ingredients. Available in two forms: 0.5-2 kg and 10 kg. Not for use in dogs with liver disease, ocular cysticercosis and spinal neurocysticercosis. | 50-60 rub. per capsule. |
Dirofen | An abundance of forms and dosages: available in the form of tablets, suspensions and pastes. There are varieties for puppies, small breed dogs and large dogs. | Tablets: 135 rub. – for small and medium breeds, 355 rub. – for large dogs. Suspension for puppies or adults: 190 rub. Pasta: 195 rub. for adult dogs, 155 rub. for puppies. |
Cestal Plus | Produced in the form of 10 kg tablets. There is an unflavored variety and a liver-flavored variety. | 120 rub. for 1 tablet. |
Dehinel Plus | Synonymous with Drontal in composition and release forms. | 260 rub. for 2 tablets per 10 kg, 440 rub. for 2 tablets per 35 kg. |
Kanikquantel | Contains fenbendazole and praziquantel. Available in 2 forms: 10 kg and 20 kg. Prohibited for puppies under 3 weeks of age. | Tablet for 10 kg - 70 rubles, for 20 kg - 165 rubles. |
Procox | Analogue of Drontal Junior. Also released. But it contains other active ingredients: emodepside (0.9 mg/ml) and toltrazuril (18 mg/ml). Active against nematodes and coccidia. The taste is improved by adding sunflower oil. | RUB 1,550 per 20 ml bottle; 680 rub. per 7.5 ml bottle. |
Drontal plus for dogs
They produce 2 types of tablets - for dogs weighing up to 10 kg and animals weighing 35 kg. Drontal Plus is intended for quarterly preventive deworming or treatment. In case of high infestation, the drug is repeated after 7-14 days. To exterminate Giardia, Drontal Plus is fed for 3 days in a row.
The number of tablets for dogs of different weights is dosed according to the following scheme:
Weight, kg | 10 kg tablet | 35 kg tablet |
>2<5 | 0,5 | |
>5<10 | 1 | |
>10<20 | 2 | |
>20<30 | 3 | |
>30<40 | 1 | |
>40<50 | 1 | 1 |
>50<60 | 2 | 1 |
>60 | 2 |
Drontal Plus is not prescribed to females for the first 2/3 of pregnancy. And also for puppies and adult pets weighing less than 2 kg. With high infestation, vomiting, diarrhea and salivation may occur due to poisoning by parasite decomposition products. In this case, detoxification therapy is indicated.
The cost of packaging in February 2021 is 386 rubles.
Price of medicine
The cost of the drug depends on the number of tablets in the pack. The price of a package of medicine, which contains two tablets, ranges from 209 to 400 rubles. The cost of a pack of Drontal plus with six tablets is 320-1100 rubles. A package of Drontal plus XL for dogs costs from 625 rubles. The average price of a medicine is 800 rubles.
Sources
- https://dog-care.ru/zdorove/lekarstva/drontal.html
- https://PetGuru.ru/zdorovie/drontal-dlya-sobak
- https://pets2.me/bok/326-drontal-ot-gelmintov-kak-davat-sobake.html
- https://dogipediya.ru/veterinariya/preparaty/drontal-plyus-dlya-sobak
- https://kupipet.ru/articles/drontal-plyus-dlya-sobak-instruktsiya-po-primeneniyu.html?sphrase_id=393
- https://usobaki.com/drontal-plus-for-dogs/
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